Deliberately low-risk

Three steps — and you own everything we produce

Start with a bounded, fixed-fee assessment, scale into ongoing oversight when you're ready, and engage embedded leadership only if you need it. Every model leaves the roadmap and records in your hands — whichever track fits your program.

Book a call
One arc, every engagement

Assess. Prove. Run.

Whatever seat you sit in, every engagement follows the same deliberately low-risk arc. Most start at Step 1, where the risk is lowest: if the assessment finds you in good shape, we will say so — and the roadmap is still yours.

Step 1 · Assess

A fixed-fee assessment

Your program, your operation, or your AI exposure — honestly mapped, with a graded roadmap you own outright. Valuable whoever executes it.

3–4 weeks · fixed fee

Step 2 · Prove

A bounded first deliverable

A signal framework, a protocol review, a governed AI pilot, a credentialed pod — one fixed scope, one measured outcome, before anything scales.

Fixed scope · fixed fee

Step 3 · Run

Senior oversight, ongoing

Named reviewers, embedded counsel, or an enablement retainer — running alongside your work, scaled to activity, documented by default.

Ongoing · retainer

The same arc, in your seat

What the three steps look like on your track

Sponsors

Safety governance (IHASG)

  1. 1Readiness Assessment — a graded gap analysis across your five safety domains, with a remediation roadmap to Level 4
  2. 2Signal Definition & Pre-IND — regulator-ready signal criteria (CRS, ICANS, DLTs) mapped to your data
  3. 3Continuous Medical Oversight — a named physician reviewer on the Workbench, every decision audit-ready
The IHASG model →
Sponsors

Emerging-biotech development

  1. 1Program Assessment — design, regulatory path, safety setup, and AI exposure, honestly graded
  2. 2Foundational deliverables — the protocol, the briefing package, the governance design, each bounded and fixed-fee
  3. 3Senior oversight — ongoing medical, regulatory, and technology counsel beside your lean team
For emerging biotech →
Service providers

CRO & FSP enablement

  1. 1Maturity Assessment — data architecture, interoperability, AI readiness, governance, future-readiness
  2. 2Lighthouse pilot — one governed use case, one modality, or one service line, with measured ROI
  3. 3Scale & institutionalize — governance hardened into your SOPs, sponsor qualifications supported
CRO & FSP enablement →
AI & regulated operations

Expert-in-the-loop review

  1. 1Review-requirement scoping — what needs a human, at what step, signed how, under which framework
  2. 2Qualified pilot — a credentialed reviewer pod on one workflow, with the assurance dossier your QA can approve
  3. 3Ongoing named review — defined SLAs, credential dossiers, a decision trail by default
Expert-in-the-loop services →

Built for

  • Teams in regulated clinical work — sponsors, CROs and FSPs, AI builders — who need judgment and proof, not just tools or headcount
  • Programs facing an inspection, a sponsor qualification, a diligence cycle, or a first-in-human milestone
  • Organizations whose AI ambitions have outrun their governance — pilots stalled at validation and sign-off
  • Leaders who want deliverables they own outright, not a retainer dependency

Not the right fit if

  • You need pure headcount staffing with no governance or specialization layer — that price war is one we deliberately sit out
  • Your program is Pre-IND with no near-term submissions — start with our free Readiness Check first
Engagement structures

How engagements are structured

However you start above, the commercial mechanics come down to two flexible structures — an ongoing retainer or a fixed-fee project — each delivered directly by the named principals.

1

Fractional Retainer Engagements

Continuous strategic partnership and on-demand access to our founders.

Advisory Retainer

Guaranteed, priority access to our founders for ongoing strategic guidance. Ideal for high-level decision support, ad-hoc "red team" reviews, and serving as an objective expert on your advisory board.

  • 10–20 hours per month of founder time
  • Priority response (within 48 hours)
  • Quarterly strategic planning sessions
  • Advisory board participation (optional)
  • Discounted rates on packaged solutions (15% off)

Embedded C-Suite (Fractional Executive)

Our founders embed within your organization as your fractional C-level resource (e.g., Fractional Chief Medical Officer, CTO, or CSO). Includes hands-on team leadership, operational oversight, and direct management of strategic initiatives.

  • 40–80 hours per month (1–2 days/week equivalent)
  • Direct team leadership and operational oversight
  • Board-level reporting and investor communications
  • Vendor and partner management oversight
  • Discounted rates on packaged solutions (25% off)

Explore the roles: Fractional CMO · Fractional CTO

2

Project-Based (Fixed-Fee)

Transparent, predictable pricing for discrete, high-impact deliverables.

Fixed-Fee Packaged Solutions

Pre-scoped engagements with defined timelines, deliverables, and pricing. No open-ended retainers, no scope creep—just decisive outcomes at critical decision points.

  • Transparent, upfront pricing
  • Defined scope, timeline, and deliverables
  • Founder-led execution (not delegated to junior staff)
  • Ideal for one-time audits, submissions, protocol design
  • No long-term commitment required
View All Packaged Solutions Below ↓

Custom Engagements: Need something outside our standard packages? We can scope custom fixed-fee engagements tailored to your unique requirements.

Not sure which model fits your needs?

Book a Strategy Call
Fixed-fee packages

Fixed-Fee Packaged Solutions

Transparent pricing, predictable timelines, and high-impact deliverables. Each package is designed to de-risk your program at critical decision points.

Clinical & Regulatory Strategy

IND/BLA/NDA "Red Team" Review

3 weeks

Comprehensive risk assessment of your regulatory submission before filing. Identify gaps, strengthen your CMC story, and anticipate agency questions.

Key Deliverable:

50-page risk assessment report + 2-hour founder-led debrief call

Phase 1/2 Protocol Design

4 weeks

End-to-end protocol design for advanced therapies including dose-escalation strategy, patient selection criteria, and regulatory-grade endpoints.

Key Deliverable:

Optimized protocol + global health authority (GHA) strategy memo

Global Health Authority Strategy

2 weeks

FDA/EMA/PMDA meeting preparation package including briefing books, anticipated questions, and regulatory positioning strategy for Type B, Type C, or pre-IND meetings.

Key Deliverable:

FDA/EMA/PMDA meeting prep package with Q&A scenarios

Safety & PV Audit

3 weeks

Comprehensive pharmacovigilance system audit to identify compliance gaps, SOPs weaknesses, and inspection-readiness across signal detection, case processing, and QPPV oversight.

Key Deliverable:

PV system gap analysis + prioritized remediation plan

AI & Technology Strategy

AI Strategy & Governance Audit

3 weeks

Vendor-agnostic assessment of your AI/ML readiness including data governance, model validation frameworks, and regulatory positioning for algorithm-driven endpoints.

Key Deliverable:

Vendor-agnostic AI roadmap + RFP template for vendor selection

Clinical SaaS Vendor Audit

3 weeks

Independent "fit-gap" analysis of clinical trial management systems, EDC platforms, or safety databases to ensure regulatory compliance and operational efficiency.

Key Deliverable:

Fit-gap analysis + vendor scorecard with implementation risk assessment

M&A Tech Integration Plan

4 weeks

Post-acquisition technology integration playbook for clinical operations, including data migration strategy, system consolidation roadmap, and Day 1/100 deliverables.

Key Deliverable:

100-day technology integration playbook with prioritized action plan

GenAI Proof-of-Concept

6 weeks

Build a working Retrieval-Augmented Generation (RAG) prototype to answer questions from your document library (protocols, SOPs, regulatory submissions) with full source traceability.

Key Deliverable:

Custom RAG tool for your document library + governance framework

Unified Flagship Offering

"Venture-in-a-Box" Audit

30 days

The ultimate pre-launch or pre-Series A audit. Both founders conduct a comprehensive end-to-end assessment of your program covering clinical strategy, regulatory positioning, technology infrastructure, partner readiness, and fundraising positioning.

Key Deliverable:

100+ page board-ready report + 30-day prioritized action plan across clinical, regulatory, technology, and partner domains

Concrete outputs

What you'll have when we're done

Every engagement ends with deliverables you own outright — not a retainer dependency. The names change by track; the standard doesn't.

Step 1 · Assess
  • A graded report — your safety domains, program readiness, or operational maturity, honestly scored
  • A prioritized roadmap — sequenced by risk and execution effort, usable whoever executes it
  • A founder-led debrief — findings walked through, questions answered, next steps defined

3–4 weeks · fixed fee · yours to keep

Step 2 · Prove
  • The deliverable itself — signal criteria, a protocol, a governed pilot with measured results, or an assurance dossier
  • Validation evidence mapped to your quality framework — built for your QA, or your sponsor's
  • Regulator- and buyer-ready formatting — filed, qualified, or demoed, not shelved

Fixed scope · fixed fee · yours to keep

Step 3 · Run
  • Named experts documented in your plans, SOPs, and qualification packages
  • Work signed and audit-ready as it happens — who, when, what criteria, what outcome
  • Periodic summaries — inspection-ready, exportable, yours to file

Ongoing · retainer, scaled to activity

Ready to start? Scope your first engagement on one call — no commitment required.