The AI era of clinical development

The work is moving to AI. The accountability isn't.

Every AI-accelerated protocol, signal, and submission still needs a qualified human who decides — and proof that they did.

AyurDatta is that layer: physician-led safety governance for sponsors, modernization and credentialing for CROs and FSPs, and named, credentialed experts wherever AI output must stand up to a regulator, a partner, or a buyer.

The ground is moving

Three forces arrived at once

Regulators went real-time, AI outran its own governance, and the people who can run both became the scarcest asset in the industry. Whichever seat you sit in, the same clock is ticking.

Apr 2026

Regulators went real-time

The FDA's Real-Time Clinical Trials initiative moves the industry from periodic data batches to continuous signal flow — live from the trial to the agency.

Only 22% have scaled AI

AI outran its governance

AI spread through clinical work faster than the validation, oversight, and sign-off design around it — which is why most pilots stall before production, not at the model.

The constant

Judgment doesn't compress

Regulated decisions still require a qualified human — and proof that one made the call. That is the obligation we are built to carry, in every engagement.

The flagship discipline

Safety governance — where the stakes are highest, and where we started

AI now detects and grades safety signals at machine speed — but a flag is not a decision. A named, credentialed physician must adjudicate benefit-risk, and you must be able to prove they did. Integrated High-Acuity Safety Governance (IHASG) closes that gap, running on our Medical Oversight Workbench:

  • A named, credentialed oncologist as your documented reviewer
  • Part 11-style sign-off — identity, time, and meaning locked in
  • A tamper-evident audit trail, generated as the work happens
  • Sits beside your stack — not a rip-and-replace
!

"Show me the documented physician review for these fourteen AI-flagged signals."

The inspection question every AI-assisted safety program must answer — with a name, credentials, and an audit trail.

Why AyurDatta

The judgment is the product

Unlike a CRO, we don't execute your trial — so we can impartially oversee it. Unlike a software vendor, we don't audit our own algorithm. Independence is not our limitation; it is the product — delivered by named principals, not staffed down.

1,000+
Trials Powered
eClinical platform
135
Oncology Trials Led
11 First-in-Human
27
INDs Filed
FDA · EMA · PMDA
9
NDAs Approved
Regulatory success
3
BLAs Approved
Including CAR-T
100%
Inspection Success
Zero findings

Specialist depth where the toxicity is hardest

CAR-T — CRS & ICANS Antibody-Drug Conjugates Radioligand Therapy Pediatric & elderly R/R oncology AMOIP — Acute Multi-Organ Instability Phase

Read the clinical briefings from Dr. Ashok Srivastava →

Deliberately low-risk

Three steps — and you own everything we produce

Step 1 · Assess

A fixed-fee assessment

Your program, your operation, or your AI exposure — honestly mapped, with a graded roadmap you own outright. Valuable whoever executes it.

3–4 weeks · fixed fee

Step 2 · Prove

A bounded first deliverable

A signal framework, a protocol review, a governed AI pilot, a credentialed pod — one fixed scope, one measured outcome, before anything scales.

Fixed scope · fixed fee

Step 3 · Run

Senior oversight, ongoing

Named reviewers, embedded counsel, or an enablement retainer — running alongside your work, scaled to activity, documented by default.

Ongoing · retainer

Prefer embedded leadership? Our principals are also available on a fractional basis. See all engagement models →

Whose judgment it is

Delivered by the named principals

Dr. Ashok Srivastava

Dr. Ashok Srivastava

MD, Ph.D., MBA

President & Chief Medical Officer

Board-certified oncologist and the named physician reviewer. 135 trials, 11 first-in-human, 27 INDs, 9 NDAs, 3 BLAs including AUCATZYL® (obe-cel) CD19 CAR-T. Deep CAR-T, ADC, and rare-disease toxicity expertise; DSMB/IDMC Chair for novel-modality programs.

Elias Tharakan

Elias Tharakan

 

Chief Executive & Technology Officer

Architect of the industry's first unified EDC + RTSM + eCOA + Safety suite, powering 1,000+ trials across 90+ countries. Clinical technology strategy, AI governance, and GxP-validated delivery at industry scale — the engineer behind the Workbench and the unified platform to come.

Start bounded, start fixed-fee

Bring us the hardest question your program faces.

Twenty minutes to scope the right first step — bounded, fixed-fee, and yours to keep. If we're not the right fit, we'll tell you that too.